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Pharmacological characterization of hetrombopag, a novel orally active human thrombopoietin receptor agonist

Nonpeptide thrombopoietin receptor (TPOR/MPL) agonists, such as eltrombopag, have been used to treat thrombocytopenia of various aetiologies. Here, we investigated the pharmacological properties of hetrombopag, a new orally active small‐molecule TPOR agonist, in preclinical models. Hetrombopag speci...

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Publicat a:J Cell Mol Med
Autors principals: Xie, Chengying, Zhao, Huajun, Bao, Xubin, Fu, Haoyu, Lou, Liguang
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201220/
https://ncbi.nlm.nih.gov/pubmed/30156363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13809
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