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3D Self-Organized Microvascular Model of the Human Blood-Brain Barrier with Endothelial Cells, Pericytes and Astrocytes

The blood-brain barrier (BBB) regulates molecular trafficking, protects against pathogens, and prevents efficient drug delivery to the brain. Models to date failed to reproduce the human anatomical complexity of brain barriers, contributing to misleading results in clinical trials. To overcome these...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Biomaterials
मुख्य लेखकों: Campisi, Marco, Shin, Yoojin, Osaki, Tatsuya, Hajal, Cynthia, Chiono, Valeria, Kamm, Roger D.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2018
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201194/
https://ncbi.nlm.nih.gov/pubmed/30032046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2018.07.014
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