Antimicrobial Prophylaxis for Patients Undergoing Cardiac Surgery: Intraoperative Cefazolin Concentrations and Sternal Wound Infections

This study characterizes the pharmacodynamics of antimicrobial prophylaxis and sternal wound infections following cardiac surgery. Duration of surgery and cefazolin plasma concentration during wound closure were independently associated with surgical site infection at 30 days. Furthermore, a duratio...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Zelenitsky, Sheryl A., Calic, Divna, Arora, Rakesh C., Grocott, Hilary P., Lakowski, Ted M., Lillico, Ryan, Ariano, Robert E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2018
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201110/
https://ncbi.nlm.nih.gov/pubmed/30150469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01360-18
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