Antimicrobial Prophylaxis for Patients Undergoing Cardiac Surgery: Intraoperative Cefazolin Concentrations and Sternal Wound Infections

This study characterizes the pharmacodynamics of antimicrobial prophylaxis and sternal wound infections following cardiac surgery. Duration of surgery and cefazolin plasma concentration during wound closure were independently associated with surgical site infection at 30 days. Furthermore, a duratio...

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Библиографические подробности
Опубликовано в: :Antimicrob Agents Chemother
Главные авторы: Zelenitsky, Sheryl A., Calic, Divna, Arora, Rakesh C., Grocott, Hilary P., Lakowski, Ted M., Lillico, Ryan, Ariano, Robert E.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2018
Предметы:
Pharmacology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201110/
https://ncbi.nlm.nih.gov/pubmed/30150469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01360-18
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