Antimicrobial Prophylaxis for Patients Undergoing Cardiac Surgery: Intraoperative Cefazolin Concentrations and Sternal Wound Infections

This study characterizes the pharmacodynamics of antimicrobial prophylaxis and sternal wound infections following cardiac surgery. Duration of surgery and cefazolin plasma concentration during wound closure were independently associated with surgical site infection at 30 days. Furthermore, a duratio...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Zelenitsky, Sheryl A., Calic, Divna, Arora, Rakesh C., Grocott, Hilary P., Lakowski, Ted M., Lillico, Ryan, Ariano, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201110/
https://ncbi.nlm.nih.gov/pubmed/30150469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01360-18
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