טוען...
In Vitro and In Vivo Assessment of FK506 Analogs as Novel Antifungal Drug Candidates
FK506 (tacrolimus) is an FDA-approved immunosuppressant indicated for the prevention of allograft rejections in patients undergoing organ transplants. In mammals, FK506 inhibits the calcineurin-nuclear factor of activated T cells (NFAT) pathway to prevent T-cell proliferation by forming a ternary co...
שמור ב:
| הוצא לאור ב: | Antimicrob Agents Chemother |
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| Main Authors: | , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Microbiology
2018
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6201060/ https://ncbi.nlm.nih.gov/pubmed/30181374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01627-18 |
| תגים: |
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