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Apoptotic β-cells induce macrophage reprogramming under diabetic conditions
Type 2 diabetes mellitus (T2DM) occurs when insulin-producing pancreatic β-cells fail to secrete sufficient insulin to compensate for insulin resistance. As T2DM progresses, apoptotic β-cells need to be removed by macrophages through efferocytosis that is anti-inflammatory by nature. Paradoxically,...
Shranjeno v:
| izdano v: | J Biol Chem |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6200952/ https://ncbi.nlm.nih.gov/pubmed/30213857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004565 |
| Oznake: |
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