Human T-cell leukemia virus type 1 Gag domains have distinct RNA-binding specificities with implications for RNA packaging and dimerization

Human T-cell leukemia virus type 1 (HTLV-1) is the first retrovirus that has conclusively been shown to cause human diseases. In HIV-1, specific interactions between the nucleocapsid (NC) domain of the Gag protein and genomic RNA (gRNA) mediate gRNA dimerization and selective packaging; however, the...

Full description

Saved in:
Bibliographic Details
Published in:J Biol Chem
Main Authors: Wu, Weixin, Hatterschide, Joshua, Syu, Yu-Ci, Cantara, William A., Blower, Ruth J., Hanson, Heather M., Mansky, Louis M., Musier-Forsyth, Karin
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2018
Subjects:
RNA
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6200928/
https://ncbi.nlm.nih.gov/pubmed/30217825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005531
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items