Human T-cell leukemia virus type 1 Gag domains have distinct RNA-binding specificities with implications for RNA packaging and dimerization

Human T-cell leukemia virus type 1 (HTLV-1) is the first retrovirus that has conclusively been shown to cause human diseases. In HIV-1, specific interactions between the nucleocapsid (NC) domain of the Gag protein and genomic RNA (gRNA) mediate gRNA dimerization and selective packaging; however, the...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Wu, Weixin, Hatterschide, Joshua, Syu, Yu-Ci, Cantara, William A., Blower, Ruth J., Hanson, Heather M., Mansky, Louis M., Musier-Forsyth, Karin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6200928/
https://ncbi.nlm.nih.gov/pubmed/30217825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005531
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