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Interleukin-6 is both necessary and sufficient to produce perioperative neurocognitive disorder in mice
BACKGROUND: Perioperative neurocognitive disorders (PND) result in long-term morbidity and mortality with no effective interventions available. Because interleukin-6 (IL-6), a pro-inflammatory cytokine, is consistently up-regulated by trauma, including after surgery, we determined whether IL-6 is a...
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| Gepubliceerd in: | Br J Anaesth |
|---|---|
| Hoofdauteurs: | , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Elsevier
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6200097/ https://ncbi.nlm.nih.gov/pubmed/29452810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bja.2017.11.096 |
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