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Identification of growth-coupled production strains considering protein costs and kinetic variability

Conversion of renewable biomass to useful molecules in microbial cell factories can be approached in a rational and systematic manner using constraint-based reconstruction and analysis. Filtering for high confidence in silico designs is critical because in vivo construction and testing of strains is...

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Udgivet i:Metab Eng Commun
Main Authors: Dinh, Hoang V., King, Zachary A., Palsson, Bernhard O., Feist, Adam M.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6199775/
https://ncbi.nlm.nih.gov/pubmed/30370222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mec.2018.e00080
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