MYC-Induced miR-203b-3p and miR-203a-3p Control Bcl-xL Expression and Paclitaxel Sensitivity in Tumor Cells()

Taxanes are chemotherapeutic agents used in the treatment of solid tumors, particularly of breast, ovarian, and lung origin. However, patients show divergent therapy responses, and the molecular determinants of taxane sensitivity have remained elusive. Especially the signaling pathways that promote...

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Publicat a:Transl Oncol
Autors principals: Aakko, Sofia, Straume, Anne Hege, Birkeland, Einar Elvbakken, Chen, Ping, Qiao, Xi, 'Lønning, Per Eystein', Kallio, Marko J.
Format: Artigo
Idioma:Inglês
Publicat: Neoplasia Press 2018
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Original article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6199766/
https://ncbi.nlm.nih.gov/pubmed/30359947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2018.10.001
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