Novel Mad2-targeting miR-493-3p controls mitotic fidelity and cancer cells’ sensitivity to paclitaxel

The molecular pathways that contribute to the proliferation and drug response of cancer cells are highly complex and currently insufficiently characterized. We have identified a previously unknown microRNA-based mechanism that provides cancer cells means to stimulate tumorigenesis via increased geno...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Tambe, Mahesh, Pruikkonen, Sofia, Mäki-Jouppila, Jenni, Chen, Ping, Elgaaen, Bente Vilming, Straume, Anne Hege, Huhtinen, Kaisa, Cárpen, Olli, Lønning, Per Eystein, Davidson, Ben, Hautaniemi, Sampsa, Kallio, Marko J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper: Chromosome
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914283/
https://ncbi.nlm.nih.gov/pubmed/26943585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7860
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