Comparing olive oil and C4-dietary oil, a prodrug for the GPR119 agonist, 2-oleoyl glycerol, less energy intake of the latter is needed to stimulate incretin hormone secretion in overweight subjects with type 2 diabetes

BACKGROUND/OBJECTIVE: After digestion, dietary triacylglycerol stimulates incretin release in humans, mainly through generation of 2-monoacylglycerol, an agonist for the intestinal G protein-coupled receptor 119 (GPR119). Enhanced incretin release may have beneficial metabolic effects. However, diet...

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Dettagli Bibliografici
Pubblicato in:Nutr Diabetes
Autori principali: Mandøe, Mette Johannsen, Hansen, Katrine Bagge, Windeløv, Johanne Agerlin, Knop, Filip Krag, Rehfeld, Jens Frederik, Rosenkilde, Mette Marie, Holst, Jens Juul, Hansen, Harald Severin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6199285/
https://ncbi.nlm.nih.gov/pubmed/29330461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41387-017-0011-z
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