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Optimizing glutaraldehyde-fixed tissue heart valves with chondroitin sulfate hydrogel for endothelialization and shield against deterioration

Porcine glutaraldehyde-fixed pericardium is widely used to replace human heart valves. Despite the stabilizing effects of glutaraldehyde fixation, the lack of endothelialization and the occurrence of immune reactions contribute to calcification and structural valve deterioration, which is particular...

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Detalhes bibliográficos
Publicado no:Biomacromolecules
Main Authors: Lopez-Moya, Mario, Melgar-Lesmes, Pedro, Kolandaivelu, Kumaran, Hernández, Jose María de la Torre, Edelman, Elazer R., Balcells, Mercedes
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6198652/
https://ncbi.nlm.nih.gov/pubmed/29539266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biomac.8b00077
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