Metastatic breast cancer cells overexpress and secrete miR-218 to regulate type I collagen deposition by osteoblasts

BACKGROUND: Bone is one of the most frequent metastatic sites of advanced breast cancer. Current therapeutic agents aim to inhibit osteoclast-mediated bone resorption but only have palliative effects. During normal bone remodeling, the balance between bone resorption and osteoblast-mediated bone for...

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Bibliografske podrobnosti
izdano v:Breast Cancer Res
Main Authors: Liu, Xuxiang, Cao, Minghui, Palomares, Melanie, Wu, Xiwei, Li, Arthur, Yan, Wei, Fong, Miranda Y., Chan, Wing-Chung, Wang, Shizhen Emily
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6198446/
https://ncbi.nlm.nih.gov/pubmed/30348200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-018-1059-y
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