AMSC-derived exosomes alleviate lipopolysaccharide/d-galactosamine-induced acute liver failure by miR-17-mediated reduction of TXNIP/NLRP3 inflammasome activation in macrophages

BACKGROUND: Mesenchymal stem cell (MSC)-derived exosome administration has been considered as a novel cell-free therapy for liver diseases through cell-cell communication. This study was aimed to determine the effects and mechanisms of AMSC-derived exosomes (AMSC-Exo) for acute liver failure (ALF) t...

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Bibliografische gegevens
Gepubliceerd in:EBioMedicine
Hoofdauteurs: Liu, Yanning, Lou, Guohua, Li, Aichun, Zhang, Tianbao, Qi, Jinjin, Ye, Dan, Zheng, Min, Chen, Zhi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2018
Onderwerpen:
Research paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6197728/
https://ncbi.nlm.nih.gov/pubmed/30197023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.08.054
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