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Aerosol prime-boost vaccination provides strong protection in outbred rabbits against virulent type A Francisella tularensis

Tularemia, also known as rabbit fever, is a severe zoonotic disease in humans caused by the gram-negative bacterium Francisella tularensis (Ft). While there have been a number of attempts to develop a vaccine for Ft, few candidates have advanced beyond experiments in inbred mice. We report here that...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: O’Malley, Katherine J., Bowling, Jennifer L., Stinson, Elizabeth, Cole, Kelly S., Mann, Barbara J., Namjoshi, Prachi, Hazlett, Karsten R. O., Barry, Eileen M., Reed, Douglas S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6197691/
https://ncbi.nlm.nih.gov/pubmed/30346998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0205928
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