Mitochondrial – nuclear genetic interaction modulates whole body metabolism, adiposity and gene expression in vivo

We hypothesized that changes in the mitochondrial DNA (mtDNA) would significantly influence whole body metabolism, adiposity and gene expression in response to diet. Because it is not feasible to directly test these predictions in humans we used Mitochondrial-Nuclear eXchange mice, which have recipr...

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Detalles Bibliográficos
Publicado en:EBioMedicine
Autores principales: Dunham-Snary, Kimberly J., Sandel, Michael W., Sammy, Melissa J., Westbrook, David G., Xiao, Rui, McMonigle, Ryan J., Ratcliffe, William F., Penn, Arthur, Young, Martin E., Ballinger, Scott W.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2018
Materias:
Research paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6197375/
https://ncbi.nlm.nih.gov/pubmed/30232024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.08.036
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