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In vitro rejuvenation of brain mitochondria by the inhibition of actin polymerization

The oxygen consumption rate (OCR) and cytochrome c oxidase (CcO) activity of respiratory complex IV (CIV) in brain mitochondria significantly decline in middle-aged male mice compared to younger male mice. To explore the mechanisms underlying the regulation of brain mitochondrial function, we examin...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Takahashi, Kazuhide, Miura, Yuri, Ohsawa, Ikuroh, Shirasawa, Takuji, Takahashi, Mayumi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6197264/
https://ncbi.nlm.nih.gov/pubmed/30348987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34006-5
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