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BCL2 interaction with actin in vitro may inhibit cell motility by enhancing actin polymerization
In addition to its well-defined role as an antagonist in apoptosis, we propose that BCL2 may act as an intracellular suppressor of cell motility and adhesion under certain conditions. Our evidence shows that, when overexpressed in both cancer and non-cancer cells, BCL2 can form a complex with actin...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3038088/ https://ncbi.nlm.nih.gov/pubmed/20716950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cam.5.1.13175 |
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