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RGC-32 Promotes Th17 Cell Differentiation and Enhances Experimental Autoimmune Encephalomyelitis

Th17 cells play a critical role in autoimmune diseases, including multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis. Response gene to complement (RGC)-32 is a cell cycle regulator and a downstream target of TGF-β that mediates its profibrotic activity. In this study,...

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Bibliographische Detailangaben
Veröffentlicht in:J Immunol
Hauptverfasser: Rus, Violeta, Nguyen, Vinh, Tatomir, Alexandru, Lees, Jason R., Mekala, Armugam P., Boodhoo, Dallas, Tegla, Cosmin A., Luzina, Irina G., Antony, Paul A., Cudrici, Cornelia D., Badea, Tudor C., Rus, Horea G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6197070/
https://ncbi.nlm.nih.gov/pubmed/28356385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1602158
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