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Effects of Dexmedetomidine Postconditioning on Myocardial Ischemia/Reperfusion Injury in Diabetic Rats: Role of the PI3K/Akt-Dependent Signaling Pathway

OBJECTIVE: The present study was designed to determine whether dexmedetomidine (DEX) exerts cardioprotection against myocardial I/R injury in diabetic hearts and the mechanisms involved. METHODS: A total of 30 diabetic rats induced by high-glucose-fat diet and streptozotocin (STZ) were randomly assi...

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Detalhes bibliográficos
Publicado no:J Diabetes Res
Main Authors: Cheng, Xiangyang, Hu, Jing, Wang, Ya, Ye, Hongwei, Li, Xiaohong, Gao, Qin, Li, Zhenghong
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6196799/
https://ncbi.nlm.nih.gov/pubmed/30402501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/3071959
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