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Effects of dexmedetomidine postconditioning on myocardial ischemia and the role of the PI3K/Akt-dependent signaling pathway in reperfusion injury

The present study aimed to determine whether post-ischemic treatment with dexmedetomidine (DEX) protected the heart against acute myocardial ischemia/reperfusion (I/R)-induced injury in rats. The phosphatidylinositol-3 kinase/protein kinase B(PI3K/Akt)-dependent signaling pathway was also investigat...

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Bibliografski detalji
Izdano u:Mol Med Rep
Glavni autori: CHENG, XIANG YANG, GU, XIAO YU, GAO, QIN, ZONG, QIAO FENG, LI, XIAO HONG, ZHANG, YE
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918562/
https://ncbi.nlm.nih.gov/pubmed/27221008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2016.5345
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