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N-cadherin provides a cis and trans ligand for astrotactin that functions in glial-guided neuronal migration
Prior studies demonstrate that astrotactin (ASTN1) provides a neuronal receptor for glial-guided CNS migration. Here we report that ASTN1 binds N-cadherin (CDH2) and that the ASTN1:CDH2 interaction supports cell–cell adhesion. To test the function of ASTN1:CDH2 binding in glial-guided neuronal migra...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6196552/ https://ncbi.nlm.nih.gov/pubmed/30262652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1811100115 |
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