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SCoPE-MS: mass spectrometry of single mammalian cells quantifies proteome heterogeneity during cell differentiation

Some exciting biological questions require quantifying thousands of proteins in single cells. To achieve this goal, we develop Single Cell ProtEomics by Mass Spectrometry (SCoPE-MS) and validate its ability to identify distinct human cancer cell types based on their proteomes. We use SCoPE-MS to qua...

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Bibliografische gegevens
Gepubliceerd in:Genome Biol
Hoofdauteurs: Budnik, Bogdan, Levy, Ezra, Harmange, Guillaume, Slavov, Nikolai
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6196420/
https://ncbi.nlm.nih.gov/pubmed/30343672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1547-5
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