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SCoPE-MS: mass spectrometry of single mammalian cells quantifies proteome heterogeneity during cell differentiation

Some exciting biological questions require quantifying thousands of proteins in single cells. To achieve this goal, we develop Single Cell ProtEomics by Mass Spectrometry (SCoPE-MS) and validate its ability to identify distinct human cancer cell types based on their proteomes. We use SCoPE-MS to qua...

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發表在:Genome Biol
Main Authors: Budnik, Bogdan, Levy, Ezra, Harmange, Guillaume, Slavov, Nikolai
格式: Artigo
語言:Inglês
出版: BioMed Central 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6196420/
https://ncbi.nlm.nih.gov/pubmed/30343672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1547-5
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