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The role of natural selection in shaping genetic variation in a promising Chagas Disease drug target: Trypanosoma cruzi trans-sialidase
Rational drug design creates innovative therapeutics based on knowledge of the biological target to provide more effective and responsible therapeutics. Chagas disease, endemic throughout Latin America, is caused by Trypanosoma cruzi, a protozoan parasite. Current therapeutics are problematic with w...
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| Publicado no: | Infect Genet Evol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6196115/ https://ncbi.nlm.nih.gov/pubmed/29684709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.meegid.2018.04.025 |
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