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Chronological Switch from Translesion Synthesis to Homology-Dependent Gap Repair In Vivo

Cells are constantly exposed to endogenous and exogenous chemical and physical agents that damage their genome by forming DNA lesions. These lesions interfere with the normal functions of DNA such as transcription and replication, and need to be either repaired or tolerated. DNA lesions are accurate...

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Bibliographic Details
Published in:Toxicol Res
Main Authors: Fujii, Shingo, Isogawa, Asako, Fuchs, Robert P.
Format: Artigo
Language:Inglês
Published: Korean Society of Toxicology 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6195876/
https://ncbi.nlm.nih.gov/pubmed/30370004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5487/TR.2018.34.4.297
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