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A defect in homologous recombination leads to increased translesion synthesis in E. coli
DNA damage tolerance pathways allow cells to duplicate their genomes despite the presence of replication blocking lesions. Cells possess two major tolerance strategies, namely translesion synthesis (TLS) and homology directed gap repair (HDGR). TLS pathways involve specialized DNA polymerases that a...
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| Publicat a: | Nucleic Acids Res |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5027485/ https://ncbi.nlm.nih.gov/pubmed/27257075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw488 |
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