Cystathionine-γ-lyase expression is associated with mitochondrial respiration during sepsis-induced acute kidney injury in swine with atherosclerosis

BACKGROUND: Sepsis is associated with disturbed glucose metabolism and reduced mitochondrial activity and biogenesis, ultimately leading to multiple organ dysfunction, e.g., acute kidney injury (AKI). Cystathionine-γ-lyase (CSE), the major cardiovascular source of endogenous H(2)S release, is implic...

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Detalhes bibliográficos
Publicado no:Intensive Care Med Exp
Main Authors: Merz, Tamara, Wepler, Martin, Nußbaum, Benedikt, Vogt, Josef, Calzia, Enrico, Wang, Rui, Szabo, Csaba, Radermacher, Peter, McCook, Oscar
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6195873/
https://ncbi.nlm.nih.gov/pubmed/30343340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40635-018-0208-z
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