Impact of hyperglycemia on cystathionine-γ-lyase expression during resuscitated murine septic shock

BACKGROUND: Cystathionine-γ-lyase (CSE) was shown to have a regulatory role in glucose metabolism. Circulatory shock can induce metabolic stress, thereby leading to hyperglycemia and mitochondrial dysfunction. In vitro data suggest an effect of high glucose on CSE expression. Therefore, the aim of t...

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Detalles Bibliográficos
Publicado en:Intensive Care Med Exp
Main Authors: Merz, Tamara, Vogt, Josef A., Wachter, Ulrich, Calzia, Enrico, Szabo, Csaba, Wang, Rui, Radermacher, Peter, McCook, Oscar
Formato: Artigo
Idioma:Inglês
Publicado: Springer International Publishing 2017
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471286/
https://ncbi.nlm.nih.gov/pubmed/28616781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40635-017-0140-7
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