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Impact of hyperglycemia on cystathionine-γ-lyase expression during resuscitated murine septic shock

BACKGROUND: Cystathionine-γ-lyase (CSE) was shown to have a regulatory role in glucose metabolism. Circulatory shock can induce metabolic stress, thereby leading to hyperglycemia and mitochondrial dysfunction. In vitro data suggest an effect of high glucose on CSE expression. Therefore, the aim of t...

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Detalhes bibliográficos
Publicado no:Intensive Care Med Exp
Main Authors: Merz, Tamara, Vogt, Josef A., Wachter, Ulrich, Calzia, Enrico, Szabo, Csaba, Wang, Rui, Radermacher, Peter, McCook, Oscar
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471286/
https://ncbi.nlm.nih.gov/pubmed/28616781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40635-017-0140-7
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