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Impact of hyperglycemia on cystathionine-γ-lyase expression during resuscitated murine septic shock

BACKGROUND: Cystathionine-γ-lyase (CSE) was shown to have a regulatory role in glucose metabolism. Circulatory shock can induce metabolic stress, thereby leading to hyperglycemia and mitochondrial dysfunction. In vitro data suggest an effect of high glucose on CSE expression. Therefore, the aim of t...

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Détails bibliographiques
Publié dans:Intensive Care Med Exp
Auteurs principaux: Merz, Tamara, Vogt, Josef A., Wachter, Ulrich, Calzia, Enrico, Szabo, Csaba, Wang, Rui, Radermacher, Peter, McCook, Oscar
Format: Artigo
Langue:Inglês
Publié: Springer International Publishing 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471286/
https://ncbi.nlm.nih.gov/pubmed/28616781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40635-017-0140-7
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