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Impact of hyperglycemia on cystathionine-γ-lyase expression during resuscitated murine septic shock

BACKGROUND: Cystathionine-γ-lyase (CSE) was shown to have a regulatory role in glucose metabolism. Circulatory shock can induce metabolic stress, thereby leading to hyperglycemia and mitochondrial dysfunction. In vitro data suggest an effect of high glucose on CSE expression. Therefore, the aim of t...

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Bibliographische Detailangaben
Veröffentlicht in:Intensive Care Med Exp
Hauptverfasser: Merz, Tamara, Vogt, Josef A., Wachter, Ulrich, Calzia, Enrico, Szabo, Csaba, Wang, Rui, Radermacher, Peter, McCook, Oscar
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer International Publishing 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471286/
https://ncbi.nlm.nih.gov/pubmed/28616781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40635-017-0140-7
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