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Synthesis and semi-synthesis of selenopeptides and selenoproteins

The versatile chemistry of the genetically encoded amino acid selenocysteine (Sec) is employed in Nature to expand the reactivity of enzymes. In addition to its role in biology, Sec is used in protein engineering to modify folding, stability, and reactivity of proteins, to introduce conjugations and...

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Détails bibliographiques
Publié dans:Curr Opin Chem Biol
Auteurs principaux: Liu, Jun, Cheng, Rujin, Rozovsky, Sharon
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6195835/
https://ncbi.nlm.nih.gov/pubmed/29723718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2018.04.008
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