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Electroporation-mediated Delivery of FER Gene Enhances Innate Immune Response and Improves Survival in a Murine Model of Pneumonia

Previously, we reported that electroporation-mediated (EP) delivery of the FER gene improved survival in a combined trauma-pneumonia model. The mechanism of this protective effect is unknown. In this paper, we performed a pneumonia model in C57/BL6 mice with 500 CFU of Klebsiella pneumoniae. After i...

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Détails bibliographiques
Publié dans:Gene Ther
Auteurs principaux: Dolgachev, Vladislav, Panicker, Sreehari, Balijepalli, Sanjay, McCandless, Lane Kelly, Yin, Yue, Swamy, Samantha, Suresh, MV, Delano, Matthew J., Hemmila, Mark R., Raghavendran, Krishnan, Machado-Aranda, David
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6195832/
https://ncbi.nlm.nih.gov/pubmed/29907877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41434-018-0022-y
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