Molecular Characterization of Hypoxic Alveolar Epithelial Cells After Lung Contusion Indicates an Important Role for HIF-1α

OBJECTIVE: To understand the fate and regulation of hypoxic type II alveolar epithelial cells (AECs) after lung contusion (LC). BACKGROUND: LC due to thoracic trauma is a major risk factor for the development of acute respiratory distress syndrome. AECs have recently been implicated as a primary dri...

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Detalhes bibliográficos
Publicado no:Ann Surg
Main Authors: Sherman, Matthew A., Suresh, Madathilparambil V., Dolgachev, Vladislav A., McCandless, Lane K., Xue, Xiang, Ziru, Li, Machado-Aranda, David, Shah, Yatrik M., Raghavendran, Krishnan
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010036/
https://ncbi.nlm.nih.gov/pubmed/27811509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SLA.0000000000002070
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