Activation of Hypoxia-Inducible Factor-1α in Type 2 Alveolar Epithelial Cell Is a Major Driver of Acute Inflammation Following Lung Contusion

OBJECTIVE: Lung contusion is a major risk factor for the development of acute respiratory distress syndrome. Hypoxia-inducible factor-1α is the primary transcription factor that is responsible for regulating the cellular response to changes in oxygen tension. We set to determine if hypoxia-inducible...

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Publicado no:Crit Care Med
Main Authors: Suresh, Madathilparambil V., Ramakrishnan, Sadeesh Kumar, Thomas, Bivin, Machado-Aranda, David, Bi, Yu, Talarico, Nicholas, Anderson, Erik, Yatrik, Shah M., Raghavendran, Krishnan
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245055/
https://ncbi.nlm.nih.gov/pubmed/25014067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0000000000000488
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