Unique pattern of neutrophil migration and function during tumor progression

Although neutrophils have been linked to the formation of the pre-metastatic niche, the mechanism of their migration to distant uninvolved tissues has remained elusive. We report that bone marrow neutrophils from mice with early-stage cancers exhibited much more spontaneous migration to tissues. The...

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Foilsithe in:Nat Immunol
Main Authors: Patel, Sima, Fu, Shuyu, Mastio, Jerome, Dominguez, George, Purohit, Abhilasha, Kossenkov, Andrew, Lin, Cindy, Alicea-Torres, Kevin, Sehgal, Mohit, Nefedova, Yulia, Zhou, Jie, Languino, Lucia R., Clendenin, Cynthia, Vonderheide, Robert H., Mulligan, Charles, Nam, Brian, Hockstein, Neil, Masters, Gregory, Guarino, Michael, Schug, Zachary, Altieri, Dario C., Gabrilovich, Dmitry I.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2018
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6195445/
https://ncbi.nlm.nih.gov/pubmed/30323345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-018-0229-5
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