Identification of monocyte-like precursors of granulocytes in cancer as a mechanism for accumulation of PMN-MDSCs

We have identified a precursor that differentiates into granulocytes in vitro and in vivo yet belongs to the monocytic lineage. We have termed these cells monocyte-like precursors of granulocytes (MLPGs). Under steady state conditions, MLPGs were absent in the spleen and barely detectable in the bon...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Mastio, Jérôme, Condamine, Thomas, Dominguez, George, Kossenkov, Andrew V., Donthireddy, Laxminarasimha, Veglia, Filippo, Lin, Cindy, Wang, Fang, Fu, Shuyu, Zhou, Jie, Viatour, Patrick, Lavilla-Alonso, Sergio, Polo, Alexander T., Tcyganov, Evgenii N., Mulligan, Charles, Nam, Brian, Bennett, Joseph, Masters, Gregory, Guarino, Michael, Kumar, Amit, Nefedova, Yulia, Vonderheide, Robert H., Languino, Lucia R., Abrams, Scott I., Gabrilovich, Dmitry I.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6719429/
https://ncbi.nlm.nih.gov/pubmed/31239386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20181952
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