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A novel class of ER membrane proteins regulates ER-associated endosome fission

ER membrane contact sites (MCSs) mark positions where endosomes undergo fission for cargo sorting. To define the role of ER at this unique MCS, we targeted a promiscuous biotin ligase to cargo sorting domains on endosome buds. This strategy identified the ER membrane protein TMCC1, a member of a con...

詳細記述

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書誌詳細
出版年:Cell
主要な著者: Hoyer, Melissa J., Chitwood, Patrick J., Ebmeier, Christopher C., Striepen, Jonathan F., Qi, Robert Z., Old, William M., Voeltz, Gia K.
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6195207/
https://ncbi.nlm.nih.gov/pubmed/30220460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.08.030
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