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A novel class of ER membrane proteins regulates ER-associated endosome fission

ER membrane contact sites (MCSs) mark positions where endosomes undergo fission for cargo sorting. To define the role of ER at this unique MCS, we targeted a promiscuous biotin ligase to cargo sorting domains on endosome buds. This strategy identified the ER membrane protein TMCC1, a member of a con...

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Bibliografski detalji
Izdano u:Cell
Glavni autori: Hoyer, Melissa J., Chitwood, Patrick J., Ebmeier, Christopher C., Striepen, Jonathan F., Qi, Robert Z., Old, William M., Voeltz, Gia K.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6195207/
https://ncbi.nlm.nih.gov/pubmed/30220460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.08.030
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