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Reticulon-3 promotes endosome maturation at ER membrane contact sites

ER tubules form and maintain membrane contact sites (MCSs) with endosomes. How and why these ER-endosome MCSs persist as endosomes traffic and mature is poorly understood. Here we find that a member of the reticulon protein family, Reticulon-3L (Rtn3L), concentrates ER-endosome MCSs as endosomes mat...

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Détails bibliographiques
Publié dans:Dev Cell
Auteurs principaux: Wu, Haoxi, Voeltz, Gia K.
Format: Artigo
Langue:Inglês
Publié: 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7837408/
https://ncbi.nlm.nih.gov/pubmed/33434526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2020.12.014
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