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7-Deacetyl-10-alkylthiocolchicine derivatives – new compounds with potent anticancer and fungicidal activity

A series of new semi-synthetic 7-deacetyl-10-alkylthiocolchicne derivatives with ethyl, n-propyl, i-propyl and n-butyl substituents were synthesised and characterised by spectroscopic methods, elemental analysis, DFT calculations and molecular docking simulations. All the synthesized compounds have...

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Detalhes bibliográficos
Publicado no:Medchemcomm
Main Authors: Kurek, Joanna, Kwaśniewska-Sip, Patrycja, Myszkowski, Krzysztof, Cofta, Grzegorz, Murias, Marek, Barczyński, Piotr, Jasiewicz, Beata, Kurczab, Rafał
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6195099/
https://ncbi.nlm.nih.gov/pubmed/30429975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8md00352a
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