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SMYD2 glutathionylation contributes to degradation of sarcomeric proteins

Reactive oxygen species (ROS) contribute to the etiology of multiple muscle-related diseases. There is emerging evidence that cellular stress can lead to destabilization of sarcomeres, the contractile unit of muscle. However, it is incompletely understood how cellular stress induces structural desta...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Munkanatta Godage, Dhanushka N. P., VanHecke, Garrett C., Samarasinghe, Kusal T. G., Feng, Han-Zhong, Hiske, Mark, Holcomb, Joshua, Yang, Zhe, Jin, Jian-Ping, Chung, Charles S., Ahn, Young-Hoon
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6194001/
https://ncbi.nlm.nih.gov/pubmed/30337525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06786-x
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