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Understanding molecular consequences of putative drug resistant mutations in Mycobacterium tuberculosis

Genomic studies of Mycobacterium tuberculosis bacteria have revealed loci associated with resistance to anti-tuberculosis drugs. However, the molecular consequences of polymorphism within these candidate loci remain poorly understood. To address this, we have used computational tools to quantify the...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Portelli, Stephanie, Phelan, Jody E., Ascher, David B., Clark, Taane G., Furnham, Nicholas
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6193939/
https://ncbi.nlm.nih.gov/pubmed/30337649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-33370-6
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