Identification of UHRF2 as a novel DNA interstrand crosslink sensor protein

The Fanconi Anemia (FA) pathway is important for repairing interstrand crosslinks (ICLs) between the Watson-Crick strands of the DNA double helix. An initial and essential stage in the repair process is the detection of the ICL. Here, we report the identification of UHRF2, a paralogue of UHRF1, as a...

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Foilsithe in:PLoS Genet
Main Authors: Motnenko, Anna, Liang, Chih-Chao, Yang, Di, Lopez-Martinez, David, Yoshikawa, Yasunaga, Zhan, Bao, Ward, Katherine E., Tian, Jiayang, Haas, Wilhelm, Spingardi, Paolo, Kessler, Benedikt M., Kriaucionis, Skirmantas, Gygi, Steven P., Cohn, Martin A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2018
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6193622/
https://ncbi.nlm.nih.gov/pubmed/30335751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007643
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