Transgenic overexpression of furin increases epileptic susceptibility

The proprotein convertase Furin plays crucial roles in the pathology of many diseases. However, the specific role of furin in epilepsy remains unclear. In our study, furin protein was increased in the temporal neocortex of epileptic patients and in the hippocampus and cortex of epileptic mice. The f...

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Veröffentlicht in:Cell Death Dis
Hauptverfasser: Yang, Yi, He, Miaoqing, Tian, Xin, Guo, Yi, Liu, Feng, Li, Yun, Zhang, Haiqing, Lu, Xi, Xu, Demei, Zhou, Ruijiao, Ma, Yuanlin, Wang, Wei, Chen, Guojun, Hu, Yida, Wang, Xuefeng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6193048/
https://ncbi.nlm.nih.gov/pubmed/30333479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1076-x
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