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Age-related waning of immune responses to BCG in healthy children supports the need for a booster dose of BCG in TB endemic countries

In the absence of a more effective vaccine against TB and in the interest of developing one, it is essential to understand immune responses associated with BCG protection. We comprehensively characterized T cell populations in BCG-vaccinated children over time. Blood from 78 healthy, BCG-vaccinated...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Whittaker, Elizabeth, Nicol, Mark P., Zar, Heather J., Tena-Coki, Nontobeko G., Kampmann, Beate
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6193026/
https://ncbi.nlm.nih.gov/pubmed/30333506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-33499-4
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