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A Functional Whole Blood Assay to Measure Viability of Mycobacteria, using Reporter-Gene Tagged BCG or M.Tb (BCG lux/M.Tb lux)

Functional assays have long played a key role in measuring of immunogenicity of a given vaccine. This is conventionally expressed as serum bactericidal titers. Studies of serum bactericidal titers in response to childhood vaccines have enabled us to develop and validate cut-off levels for protective...

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Detalhes bibliográficos
Main Authors: Newton, Sandra, Martineau, Adrian, Kampmann, Beate
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230178/
https://ncbi.nlm.nih.gov/pubmed/21946922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/3332
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