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DNA topoisomerase 1 and 2A function as oncogenes in liver cancer and may be direct targets of nitidine chloride

The aim of the present study was to determine the role of topoisomerase 1 (TOP1) and topoisomerase 2A (TOP2A) in liver cancer (LC), and to investigate the inhibitory effect of nitidine chloride (NC) on these two topoisomerases. Immunohistochemistry (IHC) staining and microarray or RNA sequencing dat...

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Detalhes bibliográficos
Publicado no:Int J Oncol
Main Authors: Liu, Li-Min, Xiong, Dan-Dan, Lin, Peng, Yang, Hong, Dang, Yi-Wu, Chen, Gang
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6192772/
https://ncbi.nlm.nih.gov/pubmed/30132517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2018.4531
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