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An enzymatic approach reverses nicotine dependence, decreases compulsive-like intake, and prevents relapse

Tobacco use disorder is the leading cause of disease and preventable death worldwide, but current medications that are based on pharmacodynamics have low efficacy. Novel pharmacokinetic approaches to prevent nicotine from reaching the brain have been tested using vaccines, but these efforts have fai...

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Bibliografiske detaljer
Udgivet i:Sci Adv
Main Authors: Kallupi, Marsida, Xue, Song, Zhou, Bin, Janda, Kim D., George, Olivier
Format: Artigo
Sprog:Inglês
Udgivet: American Association for the Advancement of Science 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6192681/
https://ncbi.nlm.nih.gov/pubmed/30345354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aat4751
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