A Comprehensive Analysis of SNCA−Related Genetic Risk in Sporadic Parkinson Disease

OBJECTIVE: The goal of this study was to refine our understanding of disease risk attributable to common genetic variation in SNCA, a major locus in Parkinson disease, with potential implications for clinical trials targeting α−synuclein. We aimed to dissect the multiple independent association sign...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Ann Neurol
Prif Awduron: Pihlstrøm, Lasse, Blauwendraat, Cornelis, Cappelletti, Chiara, Berge-Seidl, Victoria, Langmyhr, Margrete, Henriksen, Sandra Pilar, van de Berg, Wilma D. J., Gibbs, J. Raphael, Cookson, Mark R., Singleton, Andrew B., Nalls, Mike A., Toft, Mathias
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6192521/
https://ncbi.nlm.nih.gov/pubmed/30146727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.25274
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