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Role of HSP90 in the Regulation of de Novo Purine Biosynthesis

Despite purines making up one of the largest classes of metabolites in a cell, little is known about the regulatory mechanisms that facilitate efficient purine production. Under conditions resulting in high purine demand, enzymes within the de novo purine biosynthetic pathway cluster into multienzym...

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Détails bibliographiques
Publié dans:Biochemistry
Auteurs principaux: Pedley, Anthony M., Karras, Georgios I., Zhang, Xin, Lindquist, Susan, Benkovic, Stephen J.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6192518/
https://ncbi.nlm.nih.gov/pubmed/29553718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00140
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