MiR-133a Mimic Alleviates T1DM-Induced Systolic Dysfunction in Akita: An MRI-Based Study

Diabetic cardiomyopathy is a leading cause of heart failure. Developing a novel therapeutic strategy for diabetic cardiomyopathy and characterizing animal models used for diabetes mellitus (DM) are important. Insulin 2 mutant (Ins2(+/-)) Akita is a spontaneous, genetic, mouse model for T1DM, which i...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Nandi, Shyam Sundar, Shahshahan, Hamid Reza, Shang, Quanliang, Kutty, Shelby, Boska, Michael, Mishra, Paras Kumar
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6192327/
https://ncbi.nlm.nih.gov/pubmed/30364155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.01275
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