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Elevated Na/H exchanger 1 (SLC9A1) emerges as a marker for tumorigenesis and prognosis in gliomas

BACKGROUND: Sodium/hydrogen exchanger 1 (NHE1), encoded by the SLC9A1 gene (SoLute Carrier family 9A1) in humans, is the main H(+) efflux mechanism in maintaining alkaline intracellular pH (pH(i)) and Warburg effects in glioma. However, to date, there are no clinical studies exploring pharmacologica...

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Podrobná bibliografie
Vydáno v:J Exp Clin Cancer Res
Hlavní autoři: Guan, Xiudong, Luo, Lanxin, Begum, Gulnaz, Kohanbash, Gary, Song, Qingkun, Rao, Aparna, Amankulor, Nduka, Sun, Baoshan, Sun, Dandan, Jia, Wang
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6192309/
https://ncbi.nlm.nih.gov/pubmed/30333031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0923-z
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